The Definitive Guide to ceesdekker
The Definitive Guide to ceesdekker
Blog Article
‘The 2nd is nanopores, which can be our oldest line of exploration and that has now led to DNA sequencers dependant on nanopores. We pull unique DNA strands via a nanopore and will then examine from the nucleotide sequence. Incredibly lately, we even managed to study out a single protein for the first time applying This system. But this line of exploration is not simply about producing instruments, but in addition about actual biological questions.
Human Rad51 filaments on double- and solitary-stranded DNA: correlating frequent and irregular types with recombination functionality.
Multicolor imaging with the bacterial nucleoid and mobile division proteins with blue, orange, and around-infrared fluorescent proteins
Considering that 2000, Dekker has shifted the main emphasis of his do the job in the direction of biophysics the place he studies the Houses of one biomolecules and cells using the resources of nanotechnology. This modification of industry was driven by his fascination for your impressive performing of Organic molecular structures, in addition to with the extensive-term perspective that lots of appealing discoveries is usually expected Within this subject.[5] Recent traces of exploration in his biophysics team are during the parts of:[six]
That may be a dream of mine and we set to operate having a delightful dose of naivety. This is something which will most likely yield impressive brings about the for a longer time expression, but that doesn't make a difference. You shouldn't only want to operate on the queries of tomorrow, and also on the queries on the working day after tomorrow.’
Our analysis ranges through the biophysics of DNA to synthetic cells and past. Make sure you have a look below in the spectrum of our present projects.
Lots of related developments followed, where our group established https://www.ceesdekker.net various transistor variants including single-electron transistors at space temperature and intramolecular nanotube junctions that acted as rectifying diodes, and coupled several transistors into tiny proof-of-principle electronic circuits.
Researching DNA loop extrusion by SMC proteins for chromosome architecture with solitary-molecule assays.
The rotors harness Electricity from a nanoscale h2o and ion stream that is certainly generated by a static chemical or electrochemical opportunity gradient from the nanopore, that happen to be set up via a salt gradient or utilized voltage, respectively. These synthetic nanoengines self-Arrange and operate autonomously in physiological disorders, suggesting strategies to constructing Electricity-transducing motors at nanoscale interfaces.
But carbon nanotubes have remained a study subject of substantial curiosity to several. Certainly, the outlook on making use of carbon nanotubes to construct sensible gadgets, in areas such as radio-frequency electronics, digital electronics and versatile electronics, continues to be dazzling.
Case in point (four) of bending configurations in 3D simulations of DNA rods on nanopores. A part of the membrane is proven in grey, the rim of the pore is highlighted in pink, in addition to a 3D rendering with the motion from the DNA rod is displayed.
Cees Dekker is Distinguished College Professor at TU Delft. Qualified as a physicist, he pioneered nanotechnology with many discoveries on carbon nanotubes within the 1990s. Because 2000, he moved to single-molecule biophysics and nanobiology. His current study focuses on (i) nanopores for protein sequencing; (ii) chromosome composition, especially SMC motor protein; and (iii) creating a residing synthetic cell from lifeless molecules. Dekker is an elected member from the KNAW and fellow towards the APS and also the IOP.
You happen to be utilizing a browser that isn't supported by Fb, so we have redirected you to a simpler Variation to provde the finest practical experience.
Dekker heeft fundamentele ontdekkingen gedaan op het gebied van koolstof nanobuisjes. Mede vanwege deze werkzaamheden is hij al jaren de meest geciteerde fysicus in Nederland. Tegenwoordig onderzoekt hij achieved enkel-molecuultechnieken de biofysica van moleculen in de biologische cel. Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond intelligent style and design in 2005. (nl)